1. There is no possibility of an objective moral law because there is no possibility of a moral lawgiver. Without God to give the moral law, there is no room for an objective moral law. The only possibilities of a moral law become subjective, and relativistic--which amounts to no moral law at all. But, this doesn't coincide with what we know of ourselves as people. People think in terms of antithesis (right and wrong, black and white, yes and no), and when people attempt to defend the position of relativism, they are forced to base their reasoning on antithesis. (e.g., Relativism is right, absolutism is wrong.)
2. Atheism offers no meaning for life. The atheist philosopher Jean-Paul Sartre understood that if finite man had no infinite reference point, then finite man has no meaning, and there is no consequence or meaning to anything he does. Life is, under this philosophy, "absurd." It has no meaning. Theism offers an anchor for finite man to compare his life, his actions, and their consequences to a constant, immutable source: God. God gives life meaning.
3. Atheism cannot explain the genesis of the Universe. To believe atheism is to believe that all we know: matter, energy, motion, everything came from nothing. Nothing means absolutely nothing. Nothingness. Something cannot come from nothing. This is a philosophical problem for atheism, and atheism has no answer for this. Even if Darwinism were true, that doesn't explain what caused Darwinism.
4. Atheism has no concept of divine retribution, or just desserts. As it happens sometimes, bad things happen to good people, and good things happen to bad people. A theistic view allows that a wrongdoer will get his just desserts in the after-life. Atheism does not offer this.
5. If atheism is true, we have to explain how we as personal beings came from an impersonal Godless universe. Atheism has no coherent answer to this.
6. Atheism causes its leading advocates to viscerally hate a God they don't believe exists.
As Ravi Zacharias frequently propounds, only the Christian worldview sufficiently and coherently answers the questions of origin, condition, meaning, and destiny.